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A Study Has Linked Ibruprofen To Male Infertility, But Don't Freak Out

A Study Has Linked Ibruprofen To Male Infertility, But Don't Freak Out

A Study Has Linked Ibruprofen To Male Infertility, But Don't Freak Out

The study included 31 men, ages 18-35. A growing number of studies shed light on concerning health issues that may arise from NSAIDs and ibuprofen in particular. Epidemiological studies have shown that NSAID exposure was associated with reduced testosterone and congenital malformations; another study showed a drop in a testosterone metabolite among men who were taking ibuprofen regularly.

Ibuprofen is a popular over-the-counter drug used to alleviate pain, fever and inflammation - especially in cases of painful menstrual periods, migraines and rheumatoid arthritis.

One group was given 600mg of ibuprofen twice a day while the other group was given a placebo.

Researchers tested testicles from prostate cancer donors and cultured testes cells, which revealed that ibuprofen can affect hormones, suppressing production of testosterone through transcriptional repression, leading to compensated hypogonadism.

Scientists warn that ibuprofen could be wrecking men's fertility by making their balls shrivel up.

However, because the study is small, more research is needed to confirm the results. This repression results in the elevation of the stimulatory pituitary hormones, resulting in a state of compensated hypogonadism, a disorder associated with adverse reproductive and physical health disorders. That works out to three ibuprofen tablets per day if you're taking a typical 200mg/tablet product. The condition arises when the body has to boost levels of testosterone because normal production in the testes has fallen. It's an important finding to keep in mind-but also comes with some caveats, and isn't exactly a clarion call to ditch painkillers like ibuprofen (sold under brand names like Advil and Motrin) altogether.

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Previous research by European scientists showed that male babies whose mothers took ibuprofen experienced disturbances to their endocrine system, according to CNN.

"The safety and efficacy of active ingredients in these products has been well documented and supported by decades of scientific study and real-world use", he added. The disorder is also linked to depression and strokes, as the study's authors note.

14 of them were given daily doses of Ibuprofen, which professional and amateur athletes take.

Fortunately, the condition went away in the volunteers when they stopped taking the medication.

In the subjects, the condition was temporary, but study leads told the Guardian it could become a permanent problem in cases of long term overuse.

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